Category Archives: Email Notifications

Updated Feature: Amendment Notifications Now Include Change Summary

Study-wide and site-specific amendment email notifications have been updated to include the protocol version number (as entered by the Reviewing IRB), the automatically assigned “Revision #” when a study-wide amendment does not change the protocol, and the change summary for the amendment. That now means sIRBs and Study Managers are required to provide a description of changes when uploading site-specific amendments, as is already required for study-wide amendments. IREx recommends starting the change summary with the amendment number to help the site identify the change. This information is then embedded in the notification email to help sites and sIRBs communicate more clearly about amendments.

Updated Feature: Enhanced Study-wide and Site Amendment Email Notifications

To provide more information about amendment approvals uploaded to IREx, the study-wide and site-specific amendment approval notifications will now include the study protocol version number and the change summary, both of which are entered by the Reviewing IRB. TIPS:

  • Minimize confusion for the study teams by ensuring the “protocol version” matches the version that is listed on the protocol.
  • Increase consistency by including the amendment # from your IRB system at the beginning of the change summary.

Additionally, when uploading site-specific amendments, sIRB Liaisons or Study Managers will now be required to provide a description of the changes. TIP: We recommend starting the change summary with the amendment # to help the site identify the change.

New Feature: Manually Notify HRRPs and Investigators About Your Study in IREx

IREx now allows Reviewing IRB Liaisons and IREx Study Managers to manually notify sites about their study in IREx instead of automatically emailing sites as soon as they are added to a study. Now sites can be notified at different times if they are being onboarded at different times.

When an IREx Study Managers lists a site on a study, they will enter a PI name and email. The site will appear on the Status Summary Tab. Click the “Notify HRPP” button to notify the site HRPP (and the PI identified) of the study in IREx. This does not give the PI access to IREx. The purpose of this email is to connect the investigator to their local HRPP.

Official Documentation of Reliance Email

IREx sends an official documentation of reliance email to the Reviewing IRB Liaisons, Participating Site HRPP Liaisons and Study Team Members.

This email is sent after the Participating Site HRPP Liaison has accepted the Reviewing IRB’s study-specific reliance plan (SSRP). A PDF of the letter of reliance is attached to this email.